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How Is An SNRI Thought to Work



Serotonin and norepinephrine reuptake inhibitors (SNRIs) are a group of medications that are used to effectively treat depression. SNRI information indicates that these drugs were first introduced in the mid-1990s and have since become one of the most commonly used st john wort antidepressant medications available, even more widely used than most natural antidepressants.

Understanding How Depression Comes About

Depression has been recognized as a medical condition for hundreds of years and this syndrome, also referred to what are the common signs of depression as major depression or clinical depression, is characterized by an all-encompassing low mood as well as by a loss of interest and pleasure in normally enjoyable activities. Depression is also one of the most commonly diagnosed mental illnesses in the developed world and as a result a broad range of natural antidepressants and medications have been developed over the years in order to provide relief from these symptoms and to treat depression.

Within the United States, serotonin norepinephrine reuptake inhibitors are approved to treat depression by the Food and Drug Administration. There are many types of generic serotonin and norepinephrine reuptake inhibitors available, including venlafaxine (often sold as Effecxor), desvenlafaxine (Pristiq), duloxetine (Cymbalta and Yentreve), and milnacipran (Dalciprain, Ixel, Savella). Although there are many types of serotonin norepinephrine reuptake inhibitors, all of them are generally used in a similar way, they all work in a similar way, and have similar SNRI effects that help treat depression. However, before one is able to understand how SNRI effects can help treat depression, it is necessary to first understand one of the potential causes of this medical condition.

What Doctors Say About Depression

Many doctors and scientists believe that depression may be caused by a chemical imbalance in the brain. Within the brain, there are a number of different chemicals that are used to send messages from one nerve cell to another; most SNRI information describes these chemicals neurotransmitters.  Serotonin and norepinephrine are two of several known neurotransmitters that are used to send messages and control and regulate a person’s mood and emotions. Typically, as a message travels through the brain nerve cells release serotonin or norepinephrine, which then enter the gap between the first nerve cell and the one next to it.

Serotonin and Norepinephrine Information

After enough serotonin or norepinephrine gets to the next cell, it activates its receptors and the message continues onwards. The left over serotonin or norepinephrine is then reabsorbed by the first cell. According to available SNRI information, this process occurs without any problems, but for some people their balance of norepinephrine may be off, which affects the ability of the nerve cells to communication with each other. It is these chemicals that SNRI effects act on.

Available SNRI information explains that this class of drugs works by blocking the reuptake of serotonin and norepinephine in the brain, which causes more of these chemicals to remain in the space between brain cells and therefore improve communication between nerve cells. Many well known herbal and natural antidepressants can affect a person’s mood using this mechanism as well.